Antibiotics — Flashcards

Flashcard 421: Resistance to Isoniazid can develop due to mutations that lead to underexpression of _____

Answer: KatG

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Flashcard 422: What is the spectrum of activity for Clindamycin? _____

Answer: Gram positives; anaerobic infections above the diaphragm

Extra:   Watch Clindamycin [https://dashboard.sketchy.com/study/medical/courses/medical-pharmacology/units/medical-pharmacology-antimicrobials/videos/medical-pharmacology-antimicrobials-inhibitors-of-bacterial-protein-synthesis-clindamycin?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] https://onlinemeded.org/spa/infectious-disease?ref=anki 

Flashcard 423: Cefaclor, Cefoxitin, and Cefuroxime are _____ cephalosporins.

Answer: 2nd generation

Flashcard 424: Examples of drugs eliminated by zero-order elimination include _____, ethanol, and aspirin (high concentrations)

Answer: phenytoin

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Flashcard 425: Can you use Daptomycin to treat lung infections? _____

Answer: No

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Flashcard 426: The treatment for rickettsia species is _____

Answer: doxycycline

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Flashcard 427: TMP-SMX are contraindicated in the _____ trimester (pregnancy), due to their effects on folate metabolism

Answer: 1st

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Flashcard 428: Chloramphenicol causes a dose-_____ anemia and a dose-_____ aplastic-anemia

Answer: dependent

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Flashcard 429: Mupirocin is a topical antibiotic that works by inhibiting _____

Answer: isoleucine t-RNA synthetase

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Flashcard 430: Fluoroquinolones are contraindicated in children _____ old due to damage to growing cartilage

Answer: < 18* years

Extra:   Watch Fluoroquinolones [https://dashboard.sketchy.com/study/medical/courses/medical-pharmacology/units/medical-pharmacology-antimicrobials/videos/medical-pharmacology-antimicrobials-other-antibiotics-fluoroquinolones?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] https://onlinemeded.org?ref=anki