Antibiotics — Flashcards

Flashcard 401: Treatment of choice for *Pasteurella multocida* is _____

Answer: penicillin

Extra: *Pasteurella multocida* is a gram-negative coccobacillus commonly found in the oral cavity of dogs and cats. [Sketchy Micro Video](https://dashboard.sketchy.com/study/medical/courses/medical-microbiology/units/medical-microbiology-bacteria/videos/medical-microbiology-bacteria-gram-negative-bacilli-zoonotics-pasteurella-multocida)

Flashcard 402: Mechanism of resistance of linezolid includes a(n) _____ mutation of the _____

Answer: point

Extra: Resistance to linezolid typically occurs via a point mutation of the 23S rRNA (part of the 50S subunit), which prevents the drug from binding. Watch Linezolid: https://dashboard.sketchy.com/study/medical/courses/medical-pharmacology/units/medical-pharmacology-antimicrobials/videos/medical-pharmacology-antimicrobials-inhibitors-of-bacterial-protein-synthesis-linezolid?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical

Flashcard 403: What drug is an inhibitor of prokaryotic RNA polymerase? _____

Answer: Rifampin

Extra:   Watch Transcription and RNA Processing [https://dashboard.sketchy.com/study/medical/courses/medical-biochemistry/units/medical-biochemistry-molecular-biology/videos/medical-biochemistry-molecular-biology-rna-transcription-and-rna-processing?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] https://onlinemeded.org/spa/infectious-disease?ref=anki 

Flashcard 404: Aminoglycosides are commonly paired with _____ or vancomycin to enhance their penetration of cells

Answer: β-lactams

Extra:   Watch Aminoglycosides [https://dashboard.sketchy.com/study/medical/courses/medical-pharmacology/units/medical-pharmacology-antimicrobials/videos/medical-pharmacology-antimicrobials-inhibitors-of-bacterial-protein-synthesis-aminoglycosides?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] https://onlinemeded.org/spa/infectious-disease?ref=anki 

Flashcard 405: 1st generation cephalosporins can treat UTIs caused by what bacteria? _____

Answer: Proteus, E. coli, Klebsiella - PEcK

Extra:   Watch Cephalosporins [https://dashboard.sketchy.com/study/medical/courses/medical-pharmacology/units/medical-pharmacology-antimicrobials/videos/medical-pharmacology-antimicrobials-cell-wall-and-membrane-active-antibiotics-cephalosporins?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] https://onlinemeded.org?ref=anki 

Flashcard 406: Are Listeria, MRSA, or Enterococcus covered by 1st–4th generation cephalosporins? _____

Answer: NO

Flashcard 407: _____ are used to treat ana-erobic infections

Answer: Carbapenems

Extra:   Watch Monobactams & Carbapenems [https://dashboard.sketchy.com/study/medical/courses/medical-pharmacology/units/medical-pharmacology-antimicrobials/videos/medical-pharmacology-antimicrobials-cell-wall-and-membrane-active-antibiotics-monobactams-and-carbapenems?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] https://onlinemeded.org/spa/infectious-disease/pneumonia/acquire?ref=anki 

Flashcard 408: Clindamycin can be used to treat infection by _____; can be acquired from road-rash

Answer: Clostridium perfringens

Extra:   Watch Clindamycin [https://dashboard.sketchy.com/study/medical/courses/medical-pharmacology/units/medical-pharmacology-antimicrobials/videos/medical-pharmacology-antimicrobials-inhibitors-of-bacterial-protein-synthesis-clindamycin?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] https://onlinemeded.org/spa/infectious-disease?ref=anki 

Flashcard 409: Active Mycobacterium tuberculosis infection is treated with RIPE therapy: - R_____ - Isoniazid - Pyrazinamide - Ethambutol (or streptomycin)

Answer: ifampin

Extra:    https://onlinemeded.org/spa/renal?ref=anki  

Flashcard 410: Which antibiotic inserts itself into the cell membrane, causing depolarization of the cell membrane? _____

Answer: Daptomycin

Extra:   Watch Daptomycin [https://dashboard.sketchy.com/study/medical/courses/medical-pharmacology/units/medical-pharmacology-antimicrobials/videos/medical-pharmacology-antimicrobials-cell-wall-and-membrane-active-antibiotics-daptomycin?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] https://onlinemeded.org?ref=anki