Antibiotics — Flashcards

Flashcard 131: Which class of antimicrobials includes Gentamicin, Neomycin, Amikacin, Tobramycin, and Streptomycin? _____

Answer: Aminoglycosides

Flashcard 132: What drug can be used instead of Ethambutol to treat Mycobacteria tuberculosis infection? _____

Answer: Streptomycin

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Flashcard 133: Which two antibiotics bind to the 50S subunit of ribosomes and inhibit translocation? _____

Answer: Macrolides and Clindamycin

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Flashcard 134: What cephalosporin can bind the altered PBPs of MRSA? _____

Answer: Ceftaroline

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Flashcard 135: Mechanism of action of **Clofazimine**: Binds to _____ in bacterial DNA, preventing template function.

Answer: guanines

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Flashcard 136: Which 3rd generation Cephalosporin is used to treat meningitis and gonorrhea? _____

Answer: Ceftriaxone

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Flashcard 137: Rifampin can be remembered by the 4 R's DNA-dependent RNA polymerase inhibitor Ramps up microsomal CYP450 Red/orange body fluids Rapid _____ if used alone

Answer: Resistance

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Flashcard 138: Which protein synthesis inhibitor can cause Gray baby syndrome in infants? _____

Answer: Chloramphenicol

Flashcard 139: What nephrotoxicity is caused by Sulfonamides? _____

Answer: Acute interstitial nephritis

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Flashcard 140: Resistance to Linezolid is developed via a point mutation of _____

Answer: ribosomal RNA

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