Soft tissue tumors — Flashcards

Flashcard 1: Which type of esophageal cancer (SCC or adenocarcinoma) is associated with esophageal web (e.g. Plummer-Vinson syndrome)? _____

Answer: Squamous cell carcinoma

Flashcard 2: Myeloproliferative disorders may progress to marrow _____ or transform to acute leukemia

Answer: fibrosis

Flashcard 3: What MSK pathology is characterized histologically by a mosaic pattern of woven and lamellar bone? _____

Answer: Paget disease of bone

Flashcard 4: When performing Immunohistochemistry; a _____ stain can be used to identify Astrocytomas, Glioblastomas, Oligodendrogliomas, Ependymomas

Answer: Glial Fibrillary Acidic Protein (GFAP)

Flashcard 5: Adenomyosis grossly presents with an uniformly enlarged, soft, _____ uterus

Answer: globular

Flashcard 6: What is the most common malignant ovarian neoplasm? _____

Answer: Serous cystadenocarcinoma

Flashcard 7: What pathology may be caused by an isochromosome in the X chromosome? _____

Answer: Turner's syndrome (46,X,i(Xq))

Flashcard 8: There is an increased frequency of renal angiomyolipoma in patients with _____

Answer: tuberous sclerosis

Flashcard 9: Niemann-Pick disease

Answer:

Extra: accumulation of sphingomyelinprogressive neurodegeneration, hepatosplenomegaly, cherry-red spot on macula foam cells Ashkenazi JewAR sphingomyelinase 

Flashcard 10: Gaucher's disease

Answer:

Extra: accumulation of glucocerebrosidehepatosplenomegaly, aseptic necrosis of femur, bone crisescrumpled-paper cells Ashkenazi JewARglucocerebrosidase