Systemic Pathology — Flashcards

Flashcard 481: _____ is a pathology of collagen synthesis that may present with recurrent fractures, bowed legs, and joint hypermobility

Answer: Osteogenesis imperfecta

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Flashcard 482: Acute interstitial nephritis affects the interstitium and the renal _____

Answer: tubules

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Flashcard 483: In myelofibrosis, megakaryocytes produce excess _____ and TGF-b causing activation of fibroblasts and marrow fibrosis

Answer: platelet-derived growth factor (PDGF)

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Flashcard 484: Localized swelling in the arm following lymphatic disruption (e.g., axillary node dissection) is called _____.

Answer: lymphedema

Flashcard 485: Renal cell carcinoma is associated with _____ syndromes (e.g. ectopic EPO, ACTH, PTHrP, renin)

Answer: paraneoplastic

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Flashcard 486: _____ = ↑ risk of Alzheimer's

Answer: Down syndrome

Flashcard 487: In Osteitis Fibrosa Cystica, there are _____ tumors

Answer: brown

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Flashcard 488: What is the cause of anemia in renal failure? _____

Answer: ↓ EPO

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Flashcard 489: ASO (anti-streptolysin O) antibodies = _____

Answer: post-streptococcal glomerulonephritis

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Flashcard 490: _____ hemorrhage most commonly occurs due to rupture of Charcot-Bouchard microaneurysms, secondary to chronic hypertension

Answer: Intraparenchymal

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