Peripheral nerve disorders — Flashcards

Flashcard 1: _____ is a cutaneous disorder caused by Pseudomonas sp. that is described as rapidly progressive, necrotic cutaneous lesions.

Answer: Ecthyma Gangrenosum

Flashcard 2: Nephritic syndrome occurs due to _____ disruption

Answer: GBM

Flashcard 3: Multiple sclerosis is characterized by increased levels of _____ protein in the CSF

Answer: myelin basic

Flashcard 4: _____ is a multifocal inflammation and demyelination after infection or vaccination

Answer: Acute disseminated (postinfectious) encephalomyelitis

Flashcard 5: Histologically, patients with diabetic neuropathy will have endoneural arteriole _____

Answer: hyalinization

Flashcard 6: Guillain-Barre syndrome can arise due to the immunologic phenomenon known as _____

Answer: molecular mimicry

Flashcard 7: MEN 2A is associated with mutations in the _____ gene, which codes for receptor tyrosine kinase in cells of neural crest origin

Answer: RET

Flashcard 8: What is the term for infarcted tissue in the basal ganglia or internal capsule caused by occlusion of a lenticulostriate artery?

Answer: lacunar infarct

Flashcard 9: epidural hematoma

Answer: rupture of middle meningeal artery; fracture of temporal bone

Extra: rapid arterial bleedinglucid interval followed by decreased LOC; CN 3 palsy, increased ICPCT: biconvex, hyperdense blood; does not cross sutures; may cross falx, tentorium 

Flashcard 10: central pontine myelinolysis

Answer: often iatrogenic; caused by rapid correction of hyponatremia

Extra: massive axonal demyelination of pontine white matter tractsacute paralysis, dysarthria, dysphagia, diplopia, loss of consciousness; +/- locked-in syndromeT2 MRI: increased signal in central pons