Amyotrophic lateral sclerosis — Flashcards

Flashcard 1: Niemann Pick disease may present with progressive _____

Answer: neurodegeneration

Flashcard 2: What disease is associated with this spinal cord lesion? _____

Answer: Amyotrophic lateral sclerosis (ALS)

Flashcard 3: As limb compartment syndrome progresses, patients can develop _____ deficits

Answer: motor

Flashcard 4: Tabes Dorsalis is characterized by _____ joints due to loss of proprioception

Answer: charcot

Flashcard 5: Spongiform encephalopathy is characterized histologically by intracellular _____ due to damage to neurons and glial cells

Answer: vacuoles

Flashcard 6: Frontotemporal dementia (Pick disease) may have ubiquitinated _____ inclusions seen on histology

Answer: TDP-43

Flashcard 7: Werdnig-Hoffmann disease is the infantile form (type 1) of _____

Answer: Spinal muscular atrophy (SMA)

Flashcard 8: What lysosomal storage disease presents with central and peripheral demyelination with ataxia and dementia?_____

Answer: Metachromatic leukodystrophy

Flashcard 9: What is the term for infarcted tissue in the basal ganglia or internal capsule caused by occlusion of a lenticulostriate artery?

Answer: lacunar infarct

Flashcard 10: epidural hematoma

Answer: rupture of middle meningeal artery; fracture of temporal bone

Extra: rapid arterial bleedinglucid interval followed by decreased LOC; CN 3 palsy, increased ICPCT: biconvex, hyperdense blood; does not cross sutures; may cross falx, tentorium