Neoplasia — Flashcards

Is chronic myeloid leukemia associated with JAK2 mutations?_____

Which tumor suppressor gene is associated with neurofibromatosis type 2?_____

What inherited cancers (2) are associated with osteosarcoma? _____

What are the two single most important gene mutations associated with hereditary breast cancer? _____

Interferons stimulate antitumor activity by activating _____ Cells

'Triple-Negative' breast cancer is negative for ER, PR, and HER2/neu and has a _____ prognosis

Abnormal expression of miRNAs contributes to certain _____ (e.g. by silencing an mRNA from a tumor suppressor gene)

_____ is a cancer caused by HPV in HIV patients that often presents at the anus (in MSM's) or the cervix.

What is the key risk factor for carcinoma of urothelium (epithelium of bladder, kidney)?_____

What demographic (age group) is associated with giant cell tumor of bone? _____