Neoplasia US Medical PG Flashcards - Medical Study Cards
Master Neoplasia with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
Neoplasia Flashcard Deck - 10 Cards
Flashcard 541: _____ is a neoplastic proliferation of mature myeloid cells, especially megakaryocytes
Answer: Myelofibrosis
Extra:
Watch Myeloproliferative Neoplasms & Myelodysplastic Syndromes [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-myeloid-lymphoid/videos/medical-pathophysiology-myeloid-and-lymphoid-myeloid-disorders-myeloproliferative-neoplasms-and-myelodysplastic-syndromes?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] Watch associated Bootcamp video [https://app.bootcamp.com/med-school/hematology-and-oncology/videos/plasma-cell-dyscrasias-and-myeloproliferative-disease?index=5]
https://onlinemeded.org/spa/hematology-oncology/leukemia/acquire?ref=anki
Atlas:
Other:
Flashcard 542: Ovarian _____ is a malignant tumor composed of complex cysts with a shaggy lining of epithelium and invasion into the connective tissue
Answer: cystadenocarcinoma
Extra:
Watch Ovarian Cysts & Epithelial Ovarian Cancer [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-reproductive-gu/videos/medical-pathophysiology-reproductive-and-gu-reproductive-hormones-and-ovarian-disorders-ovarian-cysts-and-epithelial-ovarian-cancer?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org?ref=anki
Flashcard 543: The _____ carcinoma subtype of invasive ductal carcinoma is characterized by cancerous cells in a 'pool of mucus' .
Answer: mucinous
Extra: Watch Breast Cancer: https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-reproductive-gu/videos/medical-pathophysiology-reproductive-and-gu-breast-breast-cancer
https://onlinemeded.org/spa/surgery-general/breast-cancer/acquire?ref=anki
Flashcard 544: On histology, large nuclei with eosinophilic nucleoli and numerous mitotic figures is suggestive of _____
Answer: melanoma
Extra:
Watch Malignant Melanoma [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-musculoskeletal-derm/videos/medical-pathophysiology-musculoskeletal-and-derm-derm-malignant-melanoma?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] Watch associated Bootcamp video [https://app.bootcamp.com/med-school/dermatology/videos/malignant-skin-disorders?index=4]
https://onlinemeded.org/spa/surgery-subspecialty/skin-cancer/acquire?ref=anki
Flashcard 545: Myelodysplastic syndromes may be associated with a(n) _____ anomaly, which are neutrophils with bilobed nuclei
Answer: Pseudo-Pelger-Huet
Extra:
Watch Myeloproliferative Neoplasms & Myelodysplastic Syndromes [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-myeloid-lymphoid/videos/medical-pathophysiology-myeloid-and-lymphoid-myeloid-disorders-myeloproliferative-neoplasms-and-myelodysplastic-syndromes?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] Watch associated Bootcamp video [https://app.bootcamp.com/med-school/hematology-and-oncology/videos/plasma-cell-dyscrasias-and-myeloproliferative-disease?index=5]
https://onlinemeded.org/spa/heme-onc/myeloproliferative-disorders/acquire?ref=anki
Other:
Flashcard 546: In **lymphoma** (monoclonal B-cell proliferation), the normal 3:1 kappa:lambda light chain ratio will _____
Answer: change
Extra: Normally, the kappa:lambda ratio is 3:1.
- **Reactive hyperplasia**: ratio is maintained (polytypic).
- **Lymphoma**: ratio increases to >6:1 or is inverted to 1:3 (monotypic).
Flashcard 547: Medulloblastoma is a form of primitive _____ tumor (embryonic tissue origin)
Answer: neuroectodermal
Extra:
Watch Pediatric CNS Tumors [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-neuro/videos/medical-pathophysiology-neuro-intracranial-hypertension-and-tumors-pediatric-cns-tumors?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] Watch associated Bootcamp video [https://app.bootcamp.com/med-school/neurology/videos/pediatric-brain-tumors?index=4]
https://onlinemeded.org/spa/neurology?ref=anki
Medulloblastoma
T2-weighted cranial MRI (axial view) of a 7-year-old boy: isodense round lesion with hyperintense sections in the fourth ventricle (green overlay); grossly diminished gyration of the cerebellum (C). (P = poorly demarcated pons region; B = basilar artery, CS = external CSF space)
Medulloblastoma
T1-weighed cranial MRI of a 6-year-old child presenting with features of increased intracranial pressure (midsagittal section with contrast)
There is a large hypointense mass occupying the third (upper yellow overlay) and fourth (lower yellow overlay) ventricles that is causing obstructive hydrocephalus (pink overlay).
The pink overlay also highlights the leakage of CSF into the periventricular space (transependymal edema) and into the occipital lobe due to the increased intraventricular pressure.
This appearance of a fourth ventricular mass in a child is characteristic of medulloblastoma.
Medulloblastoma
Cranial MRI (T1-weighted, with contrast)
There is a mass in the posterior cranial fossa. It features solid parts (green overlay) and cystic parts (red overlay).
Location and appearance are typical of a medulloblastoma.
(D: diencephalon; P: pons; C: cerebellum; yellow outline: cerebellar tentorium)
Medulloblastoma
Photomicrograph of cerebellar vermis tissue (H&E stain)
Densely packed, small, blue anaplastic cells are present throughout the specimen. The cells have pleomorphic and hyperchromatic nuclei.
On the right, a vessel (its lumen mostly obstructed by eosinophilic material) can be seen.
These are typical histopathological findings of medulloblastoma.
Medulloblastoma
Photomicrograph of cerebellar vermis tissue (H&E stain)
Numerous small, blue, round cells with scant cytoplasm can be seen throughout the specimen (classic examples: arrows, green overlay). Their nuclei vary in size and structure (nuclear pleomorphism) and many cells feature distinctly hyperchromatic nuclei.
The majority of the cells are arranged in concentric clusters around lighter central areas consisting of neuropil (examples: dashed outlines and yellow overlay, magnified area). These clusters are referred to as Homer Wright rosettes.
These histopathological features, particularly the Homer Wright rosettes, are characteristic of a medulloblastoma.
Atlas:
Flashcard 548: _____ is the most common primary malignancy of bone in people > 40 - 50 years old
Answer: Multiple myeloma
Extra:
Watch Plasma Cell Neoplasms [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-myeloid-lymphoid/videos/medical-pathophysiology-myeloid-and-lymphoid-lymphoid-and-plasma-cell-disorders-plasma-cell-neoplasms?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] Watch associated Bootcamp video [https://app.bootcamp.com/med-school/hematology-and-oncology/videos/plasma-cell-dyscrasias-and-myeloproliferative-disease?index=2]
https://onlinemeded.org/spa/hematology-oncology/plasma-cell/acquire?ref=anki
Step 2:
Atlas:
Other:
Flashcard 549: _____ is a process by which a carcinogen damages a wide mucosal area, causing multiple tumors
Answer: Field cancerization
Extra:
https://onlinemeded.org?ref=anki
Flashcard 550: What microbe can increase the risk of gastric adenocarcinoma?
_____
Answer: H pylori
Extra:
https://onlinemeded.org/spa/gastroenterology/misc-gastric/acquire?ref=anki
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