Neoplasia US Medical PG Flashcards - Medical Study Cards
Master Neoplasia with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
Neoplasia Flashcard Deck - 10 Cards
Flashcard 491: A malignant mesenchymal tumor is a(n) _____
Answer: sarcoma
Extra: Watch associated Bootcamp video: https://app.bootcamp.com/med-school/embryology/videos/embryonic-period-weeks-3-8?index=3
https://onlinemeded.org/spa/general-physiology/cytoskeleton/acquire?ref=anki
Flashcard 492: Is polycythemia vera associated with JAK2 mutations?
_____
Answer: Yes
Extra:
* V617F is the most common mutation
Watch Myeloproliferative Neoplasms & Myelodysplastic Syndromes [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-myeloid-lymphoid/videos/medical-pathophysiology-myeloid-and-lymphoid-myeloid-disorders-myeloproliferative-neoplasms-and-myelodysplastic-syndromes?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
Watch Polycythemia [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-myeloid-lymphoid/videos/medical-pathophysiology-myeloid-and-lymphoid-myeloid-disorders-myeloproliferative-neoplasms-and-myelodysplastic-syndromes?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] Watch associated Bootcamp video [https://app.bootcamp.com/med-school/hematology-and-oncology/videos/plasma-cell-dyscrasias-and-myeloproliferative-disease?index=4]
https://onlinemeded.org/spa/hematology-oncology/leukemia/acquire?ref=anki
Other:
Flashcard 493: In the treatment of Giant Cell Tumor Of Bone, Denosumab works by binding _____, which inhibits the recruitment and activation of multinucleated giant cells.
Answer: RANKL
Extra: Denosumab is a monoclonal antibody against RANKL; it mimics the action of osteoprotegerin.
Note: In Giant Cell Tumor of Bone (GCTOB), the neoplastic stromal cells express RANKL, which then recruits and activates the reactive multinucleated giant cells (which express RANK).
Links:
- [Sketchy Pharmacology: Denosumab](https://dashboard.sketchy.com/study/medical/courses/medical-pharmacology/units/medical-pharmacology-gi-endocrine/videos/medical-pharmacology-gi-and-endocrine-thyroid-parathyroid-and-adrenal-bisphosphonates-raloxifene-denosumab-calcitonin)
- [OnlineMedEd: Immunology](https://onlinemeded.org/spa/immunology?ref=anki)
Flashcard 494: Which thyroid malignancy may arise sporadically or from progression of papillary or follicular carcinoma?
_____
Answer: Anaplastic thyroid carcinoma
Extra:
*May arise from papillary or follicular carcinoma via p53 gene mutations
Watch Thyroid Nodules & Cancer [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-endocrine/videos/medical-pathophysiology-endocrine-thyroid-and-parathyroid-thyroid-nodules-and-cancer?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org/spa/endocrine?ref=anki
Flashcard 495: Females with BRCA1 mutations have increased risk for which types of cancer?
_____
Answer: Breast, ovarian, and fallopian tube
Extra:
- These are involved in mediating dsDNA repair; BRCA 1 & 2 MCC familial pancreatic adenocarcinoma
Watch Breast Cancer [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-reproductive-gu/videos/medical-pathophysiology-reproductive-and-gu-breast-breast-cancer?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org/spa/gynecology/ovarian-cancer/acquire?ref=anki
Flashcard 496: The MYCC _____ encodes for the nuclear regulator c-myc, which stimulates cell cycle progression
Answer: proto-oncogene
Extra:
https://onlinemeded.org?ref=anki
Flashcard 497: Giant cell tumor is a locally aggressive _____ tumor
Answer: benign
Extra:
Watch Benign Bone Tumors [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-musculoskeletal-derm/videos/medical-pathophysiology-musculoskeletal-and-derm-bone-benign-bone-tumors?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org/spa/endocrine/bone-tumors/acquire?ref=anki
Flashcard 498: In regards to lung neoplasias; adenocarcinoma in situ is _____ located
Answer: peripherally
Extra:
courtyard = peripheral; prison cells are central
Watch Lung Carcinoma [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-pulmonary/videos/medical-pathophysiology-pulmonary-lung-cancer-lung-carcinoma?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] Watch associated Bootcamp video [https://app.bootcamp.com/med-school/pulmonology/videos/lung-cancer?index=6]
https://onlinemeded.org/spa/pulmonology/lung-cancer/acquire?ref=anki
Flashcard 499: Which cancer is associated with Clonorchis sinensis infection?
_____
Answer: Cholangiocarcinoma
Extra:
https://onlinemeded.org/spa/microbiology/helminths/acquire?ref=anki
Flashcard 500: _____ tumors have features in between benign and malignant
Answer: Borderline
Extra:
https://onlinemeded.org?ref=anki
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