Neoplasia US Medical PG Flashcards - Medical Study Cards
Master Neoplasia with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
Neoplasia Flashcard Deck - 10 Cards
Flashcard 201: Tumor cells can evade apoptosis / immune surveillance by downregulating expression of _____ or alternative splicing of the Fas receptor
Answer: MHC class I
Extra: Watch associated Bootcamp video [https://app.bootcamp.com/med-school/immunology/videos/t-cells?index=4]
https://onlinemeded.org?ref=anki
Flashcard 202: Follicular lymphoma is distinguished from reactive follicular hyperplasia by lack of _____ in germinal centers
Answer: tingible body macrophages
Extra:
Watch associated Bootcamp video [https://app.bootcamp.com/med-school/hematology-and-oncology/videos/leukemias-and-lymphomas?index=8]
https://onlinemeded.org/spa/hematology-oncology/lymphoma/acquire?ref=anki
Other:
Flashcard 203: Is myelofibrosis associated with JAK2 mutations?
_____
Answer: Yes (30-50%)
Extra:
Watch Myeloproliferative Neoplasms & Myelodysplastic Syndromes [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-myeloid-lymphoid/videos/medical-pathophysiology-myeloid-and-lymphoid-myeloid-disorders-myeloproliferative-neoplasms-and-myelodysplastic-syndromes?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] Watch associated Bootcamp video [https://app.bootcamp.com/med-school/hematology-and-oncology/videos/plasma-cell-dyscrasias-and-myeloproliferative-disease?index=5]
https://onlinemeded.org/spa/hematology-oncology/leukemia/acquire?ref=anki
Other:
Flashcard 204: Vinyl Chloride is a carcinogen associated with what type of cancer?
_____
Answer: Angiosarcoma of the Liver
Extra:
https://onlinemeded.org?ref=anki
Flashcard 205: Pancreatic adenocarcinoma is associated with the serum tumor markers _____ and CEA (less specific)
Answer: CA 19-9
Extra:
Watch Pancreatic Cancer & Islet Cell Tumors [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pediatrics-hepatobiliary/videos/medical-pathophysiology-hepatobiliary-pancreatic-disease-pancreatic-cancer-and-islet-cell-tumors?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] Watch associated Bootcamp video [https://app.bootcamp.com/med-school/gastroenterology/videos/pancreatic-and-biliary-pathology?index=8]
https://onlinemeded.org/spa/surgery-general/pancreas/acquire?ref=anki
Atlas:
Flashcard 206: What is the most common salivary gland tumor?
_____
Answer: Pleomorphic adenoma
Extra:
https://onlinemeded.org?ref=anki
Pleomorphic adenoma
T2-weighted axial MRI: There is a sharply demarcated, hyperintense, partially lobulated mass arising from the left retromandibular fossa, filling the entire left parapharyngeal space. The lesion is surrounded by a hypointense capsule. This finding is a pleomorphic adenoma. Differential diagnoses include other tumors of the parotid gland.
Pleomorphic adenoma
Oral cavity of a patient, ventral view: A protrusion of the left lateral wall of the pharynx can be seen. Further diagnostics performed on the patient confirmed a pleomorphic adenoma of the parotid gland, which expanded into the parapharyngeal space.
Pleomorphic adenoma of the parotid gland
Photomicrograph of parotid gland tissue (H&E stain)
On the left, there is a hypercellular area made up of round epithelial cells with hyperchromatic nuclei and narrow, spindle-shaped myoepithelial cells with flattened nuclei. On the right, there is a paucicellular area predominantly made up of hyalinized stroma (pink acellular material).
This mixed pattern of epithelial (epithelial and myoepithelial cells) and mesenchymal (stroma) components within a salivary gland tumor is pathognomonic for pleomorphic adenoma.
Atlas:
Flashcard 207: Biopsy of nasopharyngeal carcinoma usually reveals pleomorphic _____-positive epithelial cells in a background of lymphocytes
Answer: keratin
Extra:
https://onlinemeded.org?ref=anki
Flashcard 208: Breast Cancer Assessment: _____ is a receptor located on the cell membrane.
Answer: HER-2 (c-erbB2)
Extra: HER2/neu (c-erbB2) is a receptor tyrosine kinase. Overexpression is assessed via immunohistochemistry (IHC) or FISH.
https://onlinemeded.org/spa/surgery-general/breast-cancer/acquire
Flashcard 209: Renal cell carcinoma may invade the renal vein, then IVC, before spreading _____
Answer: hematogenously
Extra:
Watch Renal Cell Carcinoma & Nephroblastoma [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-renal/videos/medical-pathophysiology-renal-renal-cancer-renal-cell-carcinoma-and-nephroblastoma?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org/spa/nephrology?ref=anki
Atlas:
Flashcard 210: Seborrheic keratosis is characterized histologically by _____
Answer: keratin pseudocysts (horn cysts)
Extra:
Watch Actinic Keratosis, Squamous Cell Carcinoma & Basal Cell Carcinoma [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-musculoskeletal-derm/videos/medical-pathophysiology-musculoskeletal-and-derm-derm-actinic-keratosis-squamous-cell-carcinoma-and-basal-cell-carcinoma?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] Watch associated Bootcamp video [https://app.bootcamp.com/med-school/dermatology/videos/additional-dermatologic-disorders?index=6]
https://onlinemeded.org/spa/dermatology/hyperpigmentation/acquire?ref=anki
Atlas:
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