Neoplasia — Flashcards

Small (oat) cell carcinoma is _____ located

Grade _____ follicular lymphoma is characterized by a mixture of small cleaved cells and large noncleaved cells

Which tumor suppressor gene is associated with von Hippel-Lindau disease?_____

Which subtype of Hodgkin lymphoma is usually seen (strongest association) in the elderly and HIV+ individuals? _____

In invasive carcinoma, cell-cell contacts are lost by inactivation of _____

Erythroplakia is highly suggestive of squamous cell _____ (hyperplasia or dysplasia)

What three genetic alterations are commonly associated with papillary thyroid carcinoma?

HPV-related vulvar carcinoma arises from _____, a dysplastic precursor lesion characterized by koilocytic change, disordered cellular maturation, nuclear atypia, and increased mitotic activity

What pathology is characterized by a deficiency of the enzymes used in mismatch base repair? _____

Do both alleles of a tumor suppressor gene need to be mutated in order for expression of disease?_____