Red blood cell disorders — Flashcards

Flashcard 1: -thalassemia major may be associated with _____ RBCs on blood smear

Answer: nucleated (feature)

Flashcard 2: Folate deficiency is characterized by _____ neutrophils

Answer: hypersegmented

Flashcard 3: Does non-megaloblastic macrocytic anemia present with hypersegmented neutrophils? _____

Answer: No

Flashcard 4: What pathologic RBC finding is seen in a peripheral smear with lead and arsenic poisoning, sideroblastic anemia, thalassemia and myelodysplastic syndrome? _____

Answer: Basophilic stippling

Flashcard 5: _____ anemia occurs due to damage of RBCs as they pass through obstructed or narrowed vessels (e.g. due to microthrombi)

Answer: Microangiopathic hemolytic

Flashcard 6: Hereditary spherocytosis is primarily characterized by _____ hemolysis

Answer: extravascular

Flashcard 7: Is polycythemia vera associated with JAK2 mutations?_____

Answer: Yes

Flashcard 8: In G6PD deficiency, Heinz bodies are removed from RBCs by splenic macrophages, resulting in formation of _____ cells

Answer: bite

Flashcard 9: Renal cell carcinoma may present with paraneoplastic syndromes, such as secondary _____ (hematocrit levels)

Answer: polycythemia

Flashcard 10: testicular lymphoma

Answer: mets from primary lymphoma

Extra: poor; aggressiveolder men