CD4 monitoring and viral load — Flashcards

Flashcard 1: HIV initially infects what cell type?_____

Answer: Macrophages

Flashcard 2: Which gene is mutated in HIV protease inhibitor resistance?_____

Answer: pol gene

Flashcard 3: Which AIDS opportunistic infection stains acid-fast?_____

Answer: Mycobacterium avium complex

Flashcard 4: Which immune cell has the cell surface protein CXCR4? _____

Answer: T cells (late HIV infection)

Flashcard 5: HIV later on infects what cell type?_____

Answer: CD4+ Helper T cells

Flashcard 6: _____ is a regulatory protein of HIV that regulates viral RNA transport of unspliced viral transcripts out of the nucleus

Answer: Rev

Flashcard 7: Does HIV have an envelope?_____

Answer: Yes

Flashcard 8: progressive multifocal leukoencephalopathy (PML)

Answer:

Extra: destruction of oligodendrocytes, demyelination of CNSrapidly progressive, usually fatalrecent JC virus infection, AIDS

Flashcard 9: The _____ blot *used to be* the confirmatory test for HIV after a positive ELISA

Answer: Western

Extra:   https://onlinemeded.org/spa/infectious-disease/hiv/acquire?ref=anki 

Flashcard 10: Which HIV gene encodes for the virion p24 (Capsid) and p17 (Matrix) core proteins? _____

Answer: gag

Extra:    https://onlinemeded.org/spa/microbiology/antivirals/acquire?ref=anki