Systemic lupus erythematosus — Flashcards

Flashcard 1: Which SLE antibody is a useful predictor of disease activity and renal involvement? _____

Answer: Anti-dsDNA antibodies

Flashcard 2: Antiphospholipid syndrome can occur as a primary disorder, or as a secondary disorder (e.g. with _____)

Answer: SLE

Flashcard 3: Which antibody is sensitive for drug-induced lupus? _____

Answer: Anti-histone antibodies

Flashcard 4: Which antibody is sensitive, but not specific for SLE? _____

Answer: Antinuclear antibodies (ANA)

Flashcard 5: What anti-ribonucleoprotein antibodies are associated with Sjogren syndrome? _____

Answer: anti-SSA (Ro) and SSB (La) antibodies (... (..))

Flashcard 6: Which chemotherapeutic drug is used in the treatment of lupus nephritis?_____

Answer: Mycophenolate mofetil

Flashcard 7: multiple sclerosis

Answer: autoimmune

Extra: demyelination of CNSrelapsing and remitting symptoms including: optic neuritis, MLF syndrome, hemiparesis, hemisensory loss, bladder/bowel incontinence, scanning speech, intention tremor, nystagmusoligoclonal IgG in CSFMRI: periventricular plaquescore: β-interferon, immunosuppression, natalizumab symptomatic: antimuscarinic (incontinence), baclofen (spasticity), opiods (pain) whites, females, age 20-30