Sickle cell disease — Flashcards

Flashcard 1: Diagnosis of sickle cell anemia is confirmed by hemoglobin _____

Answer: electrophoresis (test)

Flashcard 2: What are the top two causes of osteomyelitis in sickle cell disease patients? _____

Answer: Salmonella (#1) and S. aureus

Flashcard 3: Vaso-occlusive infarcts in the pulmonary microcirculation due to sickle cell anemia causes _____

Answer: acute chest syndrome

Flashcard 4: Hydroxyurea is used in the treatment of hematological malignancies, particularly _____ disorders

Answer: myeloproliferative

Flashcard 5: What complication of sickle cell anemia presents with chest pain, SOB, and lung infiltrates? _____

Answer: Acute chest syndrome

Flashcard 6: Which blood transfusion therapy is used to increase Hb and O2 carrying capacity?_____

Answer: Packed RBCs

Flashcard 7: One complication of sickle cell anemia is auto-_____

Answer: splenectomy

Flashcard 8: Thalassemia is an inherited mutation that protects carriers against _____ malaria

Answer: Plasmodium falciparum

Flashcard 9: priapism

Answer: spinal trauma, sickle cell disease, medications

Extra: painful, sustained erection not associated with sexual desire or stimulation

Flashcard 10: hemorrhagic stroke

Answer:

Extra: HTN, anticoagulation, neoplasia, recent ischemic stroke