Hypothyroidism — Flashcards

Flashcard 1: Which thyroid imbalance presents with weight gain and decreased appetite?_____

Answer: hypothyroidism

Flashcard 2: In which disorder (hyper- or hypothyroidism) may a patient present with a goiter? _____

Answer: Both!

Flashcard 3: _____ is an autoimmune disorder that initially causes a hyperthyroidism that then becomes a hypothyroidism.

Answer: Hashimoto's Thyroiditis

Flashcard 4: Which thyroid imbalance presents with increased TSH (if 1*) and decreased free T3 / T4?_____

Answer: Hypothyroidism

Flashcard 5: A _____ multinodular goiter occurs when a multinodular goiter has hyperfunctioning follicular cells that work independently of TSH, causing increased release of T3 and T4

Answer: toxic

Flashcard 6: Kallmann syndrome

Answer: defective migration of GnRH cells

Extra: anosmia, lack of secondary sex characteristicsdecreased: GnRH, FSH, LH, testosterone, sperm count

Flashcard 7: hypogonadotropic hypogonadism

Answer:

Extra:  decreased: LH, testosterone 

Flashcard 8: primary hypogonadism

Answer:

Extra: increased: LH decreased: testosterone 

Flashcard 9: androgen insensitivity syndrome

Answer: defect in andogen receptor

Extra: female external genitalia, rudimentary vagina, internal testes, scant sexual hairincreased: testosterone, LH, estrogen46, XY i.e. normal male

Flashcard 10: 5α-reductase deficiency

Answer:

Extra: inability to convert testosterone to DHTmale internal genitalia, ambiguous external genitalia until pubertynormal: testosterone, estrogen increased: LH (or normal) AR