Evidence basis for screening recommendations — Flashcards

Flashcard 1: One positive screening test for Cushing syndrome is an increased midnight _____ cortisol

Answer: salivary

Flashcard 2: One positive screening test for Cushing syndrome is an increased free _____ on 24-hour urinalysis

Answer: cortisol

Flashcard 3: Which glucose test is the preferred screening method for gestational diabetes / CF-diabetes?_____

Answer: 2 hour oral glucose test

Flashcard 4: Levels of Prostate Specific Antigen and Digital Rectal Exam are used as screening tools to detect Prostate Carcinoma before it _____

Answer: spreads

Flashcard 5: A decreased % of which form of PSA is suggestive of prostatic adenocarcinoma? _____

Answer: Free-PSA (cancer makes bound-PSA)

Flashcard 6: With respect to TB, what does a positive PPD indicate?

Answer: current infection, past exposure, BCG vaccinated

Flashcard 7: lead-time bias

Answer: early detection confused with increased survival (e.g. cancer screening)

Flashcard 8: sensitivity (epidemiology)

Answer: The probability that a test detects disease when disease is present.

Extra: Sens = TP/(TP+FN)

Flashcard 9: specificity (test parameter)

Answer: The probability that a test indicates non-disease when disease is absent.

Extra: Spec = TN/(TN+FP)

Flashcard 10: One use of Mammography as a screening tool is to detect invasive carcinoma before it becomes _____

Answer: clinically palpable

Extra:  https://onlinemeded.org?ref=anki