Transcription/translation US Medical PG Flashcards - Medical Study Cards
Master Transcription/translation with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
Transcription/translation Flashcard Deck - 10 Cards
Flashcard 131: RNA _____ uses dsRNA complementary to an mRNA of interest to "knock down" gene expression
Answer: interference
Flashcard 132: The initial mRNA of eukaryotes contains _____ and _____, which undergo splicing
Answer: introns
Extra:
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Flashcard 133: Within an enhancer, there are domains known as _____, to which specific transcription factors bind
Answer: response elements (RE)
Extra:
Watch associated Bootcamp video [https://app.bootcamp.com/med-school/genetics/videos/dna-replication-transcription-and-translation?index=4]
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Flashcard 134: A Northern blot is useful for studying gene _____
Answer: expression
Extra:
Watch associated Bootcamp video [https://app.bootcamp.com/med-school/genetics/videos/laboratory-techniques?index=4]
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Flashcard 135: In the first step of peptide hormone synthesis, the _____ is synthesized in the rough endoplasmic reticulum (RER), directed by specific mRNA.
Answer: preprohormone
Extra: Peptide hormone synthesis begins with translation of mRNA into a preprohormone on ribosomes of the rough endoplasmic reticulum (RER).
- **Preprohormone**: Synthesized in RER
- **Prohormone**: Signal sequence cleaved in RER
- **Hormone**: Final processing in Golgi and storage in vesicles
Flashcard 136: What type of oncogene is c-MYC, N-MYC, L-MYC?
_____
Answer: Transcription factor (nuclear regulator)
Extra:
https://onlinemeded.org?ref=anki
Flashcard 137: tRNA is joined with its specific amino acid via the enzyme _____
Answer: aminoacyl-tRNA synthetase
Extra:
Watch Protein Synthesis [https://dashboard.sketchy.com/study/medical/courses/medical-biochemistry/units/medical-biochemistry-molecular-biology/videos/medical-biochemistry-molecular-biology-protein-protein-synthesis?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]Watch associated Bootcamp video [https://app.bootcamp.com/med-school/genetics/videos/dna-replication-transcription-and-translation?index=8]
https://onlinemeded.org?ref=anki
Flashcard 138: Lac Operon: What is the expression level of the Lac genes in the presence of low glucose and lactose available?
_____
Answer: Strong expression
Extra:
Watch Lac Operon [https://dashboard.sketchy.com/study/medical/courses/medical-biochemistry/units/medical-biochemistry-molecular-biology/videos/medical-biochemistry-molecular-biology-dna-lac-operon?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]Watch associated Bootcamp video [https://app.bootcamp.com/med-school/genetics/videos/dna-replication-transcription-and-translation?index=12]
https://onlinemeded.org?ref=anki
Flashcard 139: Does prokaryotic mRNA have post-transcriptional processing?
_____
Answer: No
Extra:
https://onlinemeded.org?ref=anki
Flashcard 140: The N-terminal signal sequence of a newly synthesized protein is bound by a(n) _____, which attaches the complex to the ER membrane
Answer: signal recognition particle (SRP)
Extra:
https://onlinemeded.org?ref=anki
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