Notch signaling pathway — Flashcards

Flashcard 1: A Northern blot is useful for studying gene _____

Answer: expression

Flashcard 2: McCune-Albright syndrome is due to a mutation affecting _____ signaling

Answer: G-protein

Flashcard 3: Which cytokine(s) utilize receptor tyrosine kinase signaling pathways?_____

Answer: TGF-

Flashcard 4: Tumor suppressor genes _____ cell growth

Answer: regulate

Flashcard 5: What type of receptor do growth hormones use for their signaling pathways? _____

Answer: Receptor associated tyrosine kinases

Flashcard 6: Neurofibromin (from NF1) is a Ras _____

Answer: GTPase activating protein (GAP)

Flashcard 7: TRH acts on which signalling cascade? _____

Answer: IP3

Flashcard 8: NADPH oxidase

Answer: respiratory burst

Extra: O2O2-

Flashcard 9: Give the pathway by which glucagon/Epi regulate glycogen.

Answer: glucagon/Epi, adenylyl cyclase, cAMP, protein kinase A, glycogen phosphorylsae kinase, glycogen phosphorylase

Flashcard 10: Give the pathway by which insulin regulates glycogen.

Answer: insulin, tyrosine kinase receptor, protein phosphatases, inactivated glycogen phosphorylase kinase and glycogen phorphorylase