Molecular Genetics — Flashcards

_____ describes the increased severity or earlier onset of a disease in succeeding generations

The most common type of Charcot-Marie-Tooth (CMT1A) is a duplication of large region of 17p which results in a mutation of _____

In females, one of two X-chromosomes is condensed and its genes turned off by _____, forming heterochromatin (lyonization)

Is DNA synthesis high or low fidelity? _____

What two types of variations in DNA are detected when using microarrays? (DNA markers)_____

The NF1 tumor suppressor gene normally codes for neurofibromin, a negative regulator of _____

What enzyme is targeted by anti-Scl-70 antibodies? _____

Addition of _____ will degrade any naked DNA present in a culture medium, inhibiting any bacterial transformation

What class of DNA mutations are characterized by a single nucleotide change? _____

What kind of inheritance do patients with androgenetic alopecia exhibit?_____