Molecular Genetics — Flashcards

IPEX syndrome is due to a genetic deficiency of _____

Microarrays use a _____ probe, which is hybridized to the chip, and a scanner detects the relative amounts of complementary binding

Which pyrimidine is characterized by no amino group at the 12 o'clock position AND no methyl group(s)?_____

Which cell cycle checkpoint is blocked by p53?_____

Once hyperphosphorylated, Rb releases the E2F transcription factor which initates the _____ phase

Drugs that block DNA replication often have a modified _____, preventing addition of the next nucleotide ("chain termination")

Sickle cell anemia is caused by a mutation in the _____ chain of hemoglobin

What class of diseases is Fragile X syndrome a part of?_____

_____ uses a fluorescent DNA/RNA probe to bind to a specific gene of interest on chromosomes

One feature of the genetic code is that it is _____: genetic code is conserved throughout evolution