Molecular Genetics — Flashcards

What DNA-binding motif is common to cAMP response element binding (CREB) proteins? _____

One feature of the genetic code is that it is _____: most amino acids are coded by multiple codons

The APC tumor suppresor regulates the Wnt signalling pathway by destroying _____ in the absence of a Wnt receptor-ligand interaction

The defective Menkes protein (Menkes disease) leads to decreased activity of the enzyme _____

A _____ is a base plus a sugar (ribose or deoxyribose)

The _____ is a Y-shaped region along the DNA template where leading and lagging strands are synthesized

mTOR is a _____

Sickle cell trait results in _____ 50% HbS in RBCs

What is the mode of inheritance of Fabry disease?_____

Topoisomerase _____ induces breaks in both the positive and negative DNA strands (double stranded breaks)