Molecular Genetics — Flashcards

Are the Bcl-2 related proteins Bcl-2 and Bcl-x pro- or anti-apoptotic? _____

Gel electrophoresis separates fragments on the basis of _____

Which pyrimidine is characterized by the presence of methyl groups, but no amino group at the 12 o'clock position?_____

What type of oncogene is ABL?_____

What form of chromatin is transcriptionally inactive and sterically inaccessible? _____

Topoisomerase _____ induces breaks in both the positive and negative DNA strands (double stranded breaks)

What is the mode of inheritance of Fabry disease?_____

Sickle cell trait results in _____ 50% HbS in RBCs

A _____ is a base plus a sugar (ribose or deoxyribose)

A _____ is detected with FISH as an extra site of fluorescence on one chromosome relative to its homologous chromosome