Molecular Genetics — Flashcards

Which tumor suppressor genes are associated with colon cancer?_____

Patients with kallmann syndrome most commonly have mutations in the _____ or FGFR-1 genes

What is the most common mode of inheritance of Alport syndrome? _____

In both Angelman syndrome and Prader-Willi syndrome, the most common abnormality is a gene _____

What class of enzymes cleaves nucleotides in the middle of a DNA strand? _____

Which hemoglobin type migrates the least far from the negative electrode on electrophoresis? _____

What tumour suppressor gene does the E6 protein from Human Papillomavirus (HPV) bind to and inhibit?_____

What chromosome is cyclin D1 located on? _____

Which protein from high-risk HPV binds to Rb (specifically p105-Rb)?_____

Which purine is characterized by no amino group at the 12 o'clock position?_____