Molecular Genetics — Flashcards

Constitutive activation of FGFR3 _____ chondrocyte proliferation

The _____ is a particular consensus sequence of base pairs in a genome where DNA replication begins

Is achondroplasia typically seen in patients with homozygous or heterozygous mutations?_____

_____ muscular dystrophy is typically due to frameshift or non-sense mutations, resulting in a truncated or absent dystrophin protein

One feature of the genetic code is that it is _____: each codon specifies only 1 amino acid

A _____ mutation occurs when a nucleotide substitution codes for a stop codon

Upregulation of _____ prevents chromosomal shortening and cell death in tumors

What type of probe is used to bind DNA/RNA when using a Southern/Northern blot? _____

A _____ is made up of a strand of DNA wrapped nearly twice around two copies of H2A, H2B, H3, and H4

If two linked genes have a recombination frequency of 15%, approximately how far apart are they?_____