Molecular Genetics — Flashcards

If a disease has an autosomal recessive inheritance pattern, it is usually _____ skip generations

Which enzymes relieve DNA supercoiling during DNA replication?_____

What sequence of nucleotides is repeated in Friedreich ataxia?_____

What is the mode of inheritance of Lesch-Nyhan syndrome? _____

Is the ALAS gene defect in congenital sideroblastic anemia an autosomal or X-linked defect? _____

What type of oncogene is cyclin D1?_____

1% of cases of Down syndrome are due to _____

Autosomal _____ diseases are often pleiotropic and variably expressive

_____ strategies in mice involve random insertion or targeted insertion/deletion within a mouse genome

What is the mode of inheritance of Liddle syndrome? _____