Molecular Genetics US Medical PG Flashcards - Medical Study Cards
Master Molecular Genetics with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
Molecular Genetics Flashcard Deck - 10 Cards
Flashcard 341: McCune-Albright syndrome is inherited in a(n) _____ fashion
Answer: non-inherited - somatic mutation
Extra:
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Flashcard 342: Signal transducers relay receptor activation to the _____ (e.g. Ras)
Answer: nucleus
Extra:
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Flashcard 343: What is the nucleoSide that is made with thymine?
_____
Answer: Thymidine
Extra:
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Flashcard 344: _____ describes phenotypic variation among individuals with the same genotype
Answer: Variable expressivity
Extra:
Watch associated Bootcamp video [https://app.bootcamp.com/med-school/genetics/videos/basics-of-clinical-genetics?index=6]
https://onlinemeded.org/spa/genetics?ref=anki
Flashcard 345: What is the mechanism that results in malignancy from the PDGFB oncogene?
_____
Answer: Overexpression
Extra:
https://onlinemeded.org?ref=anki
Flashcard 346: What class of DNA-binding motif is common to cAMP response element binding (CREB) proteins?
_____
Answer: Leucine zipper
Flashcard 347: The Ig heavy chain genes on chromosome 14 are _____ expressed
Answer: constitutively
Extra:
Watch associated Bootcamp video [https://app.bootcamp.com/med-school/hematology-and-oncology/videos/leukemias-and-lymphomas?index=8]
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Other:
Flashcard 348: What is the mode of inheritance of malignant hyperthermia?
_____
Answer: Autosomal dominant
Extra:
First Aid Pharmacology: Neuro/Psych
Watch Inhaled anesthetics, dantrolene [https://dashboard.sketchy.com/study/medical/courses/medical-pharmacology/units/medical-pharmacology-neuro-psych/videos/medical-pharmacology-neuropsych-anesthetics-and-analgesics-inhaled-anesthetics-dantrolene?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] Watch associated Bootcamp video [https://app.bootcamp.com/med-school/musculoskeletal/videos/skeletal-muscle?index=5]
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Flashcard 349: What proteins compose the type 1 collagen triple helix (encoded by the COL1A1 & COL1A2 genes)?\n_____
Answer: 2 alpha-1 chains & 1 alpha-2 chains
Extra: Type I collagen is composed of two $\alpha$1 chains and one $\alpha$2 chain. Mutations in the COL1A1 or COL1A2 genes lead to Osteogenesis Imperfecta.
Flashcard 350: A(n) _____ is negatively charged DNA wrapped around the outside of positively charged proteins called histones
Answer: nucleosome (10 nm chromatin)
Extra:
Watch Chromatin Structure [https://dashboard.sketchy.com/study/medical/courses/medical-biochemistry/units/medical-biochemistry-molecular-biology/videos/medical-biochemistry-molecular-biology-dna-chromatin-structure?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] Watch associated Bootcamp video [https://app.bootcamp.com/med-school/genetics/videos/dna-structure?index=12]
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