Molecular Genetics US Medical PG Flashcards - Medical Study Cards
Master Molecular Genetics with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
Molecular Genetics Flashcard Deck - 10 Cards
Flashcard 171: _____ describes an inheritance in which both alleles contribute to the phenotype of the heterozygote
Answer: Codominance
Extra:
Watch associated Bootcamp video [https://app.bootcamp.com/med-school/genetics/videos/basics-of-clinical-genetics?index=6]
https://onlinemeded.org/spa/genetics?ref=anki
Flashcard 172: Which immunoglobulin is released into breast milk (colostrum)?
_____
Answer: IgA
Extra:
Watch associated Bootcamp video [https://app.bootcamp.com/med-school/immunology/videos/antibodies?index=6]
https://onlinemeded.org/spa/immunology?ref=anki
Flashcard 173: How many ring(s) do pyrimidines have?
_____
Answer: One
Extra:
Watch Chromatin Structure [https://dashboard.sketchy.com/study/medical/courses/medical-biochemistry/units/medical-biochemistry-molecular-biology/videos/medical-biochemistry-molecular-biology-dna-chromatin-structure?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical] Watch associated Bootcamp video [https://app.bootcamp.com/med-school/genetics/videos/dna-structure?index=2]
https://onlinemeded.org?ref=anki
Flashcard 174: What is the most common mechanism of chromosomal aneuploidy?
_____
Answer: Meiotic nondisjunction
Extra:
https://onlinemeded.org/spa/genetics?ref=anki
Flashcard 175: β-thalassemia is often due to mutations in _____ and promoter sequences
Answer: splice sites
Extra: β-thalassemia is typically caused by point mutations in the β-globin gene (in contrast to α-thalassemia, which is usually caused by gene deletions).
Mechanisms:
* **Splice site mutations**: Lead to defective mRNA processing (can result in β⁰ or β⁺ thalassemia).
* **Promoter mutations**: Lead to decreased initiation of transcription (typically result in β⁺ thalassemia).
Note: Nonsense mutations (leading to premature stop codons) can also cause β-thalassemia, but they occur in the coding regions (exons), not the promoter.
Flashcard 176: What is the inheritance of Romano-Ward syndrome (a form of long QT syndrome)?
_____
Answer: Autosomal dominant
Extra:
Watch associated Bootcamp video [https://app.bootcamp.com/med-school/cardiology/videos/Cardiac%20Conductive%20Physiology?index=8]
https://onlinemeded.org?ref=anki
Flashcard 177: With H1, the nucleosome exists as _____ nm chromatin
Answer: 30
Extra: Watch associated Bootcamp video [https://app.bootcamp.com/med-school/genetics/videos/dna-structure?index=12]
https://onlinemeded.org?ref=anki
Flashcard 178: Dopamine in the synapse is transported back into the nerve terminal via the _____ transporter
Answer: (DAT) dopamine
Extra:
Sketchy Pharmacology: Autonomics (Indirect Sympathomimetics)
Watch Indirect sympathomimetics [https://dashboard.sketchy.com/study/medical/courses/medical-pharmacology/units/medical-pharmacology-autonomic-drugs/videos/medical-pharmacology-autonomic-drugs-sympathetic-indirect-sympathomimetics?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org?ref=anki
Flashcard 179: What is the mode of inheritance of medium chain acyl-CoA dehydrogenase (MCAD) deficiency?
_____
Answer: Autosomal recessive
Extra:
https://onlinemeded.org/spa/metabolism?ref=anki
Flashcard 180: Job (hyper-IgE) syndrome is due to a mutation in the _____ gene
Answer: STAT3
Extra:
* Part of the JAK-STAT signal transduction pathway
Watch Phagocytic Cell Disorders [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-immunology/videos/medical-pathophysiology-immunology-immunodeficiency-phagocytic-cell-disorders?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]
https://onlinemeded.org/spa/pediatrics/immunodeficiency/acquire?ref=anki
Keywords: Molecular Genetics flashcards, medical flashcards, NEET PG preparation, USMLE Step 1 flashcards, Anki alternative, spaced repetition medical, OnCourse flashcards
