Molecular Genetics — Flashcards

Flashcard 91: What is the predominant charge of DNA?

Answer: negative

Flashcard 92: What is the mode of inheritance of Gaucher disease? _____

Answer: Autosomal recessive

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Flashcard 93: _____ scores are used to calculate the probability that two loci are linked (linkage disequilibrium)

Answer: LOD

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Flashcard 94: When using ELISA, detection involves the use of a(n) _____ linked to a(n) enzyme

Answer: antibody

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Flashcard 95: What is the penetrance of neurofibromatosis I? _____

Answer: 100%

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Flashcard 96: One third of the collagen strand is made of the amino acid _____

Answer: glycine

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Flashcard 97: Factor V Leiden is due to a point mutation near the _____ site of factor V

Answer: cleavage

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Flashcard 98: The G1 restriction point of the cell cycle is regulated by the tumor suppressors _____ and _____

Answer: p53

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Flashcard 99: Topoisomerase _____ induces breaks in both the positive and negative DNA strands (double stranded breaks)

Answer: II

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Flashcard 100: A(n) _____ mutation occurs when a nucleotide substitution codes for a stop codon

Answer: nonsense

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