Drugs that block DNA replication often have a modified _____, preventing addition of the next nucleotide ("chain termination")
#2
Telomerase is a rare example where _____ activity occurs endogenously in humans
#3
Which prokaryotic polymerase has both 3 to 5' exonuclease activity and 5' to 3' exonuclease activity?_____
#4
What is another name for prokaryotic topoisomerase II? _____
#5
Topoisomerase _____ induces breaks in single strands of DNA
#6
Which enzyme is responsible for elongating the DNA strand? _____
#7
Upregulation of _____ prevents chromosomal shortening and cell death in tumors
#8
The _____ is a Y-shaped region along the DNA template where leading and lagging strands are synthesized
#9
What triplet is associated with Huntington's disease?
#10
What triplet is associated with Fragile X syndrome?
DNA replication US Medical PG Flashcards - Medical Study Cards
Master DNA replication with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.
DNA replication Flashcard Deck - 10 Cards
Flashcard 1: Drugs that block DNA replication often have a modified _____, preventing addition of the next nucleotide ("chain termination")
Answer: 3' OH
Flashcard 2: Telomerase is a rare example where _____ activity occurs endogenously in humans
Answer: reverse transcriptase (enzyme)
Flashcard 3: Which prokaryotic polymerase has both 3 to 5' exonuclease activity and 5' to 3' exonuclease activity?_____
Answer: DNA polymerase I
Flashcard 4: What is another name for prokaryotic topoisomerase II? _____
Answer: DNA gyrase
Flashcard 5: Topoisomerase _____ induces breaks in single strands of DNA
Answer: I
Flashcard 6: Which enzyme is responsible for elongating the DNA strand? _____
Answer: DNA polymerase (specifically, DNA polymerase III in prokaryotes)
Flashcard 7: Upregulation of _____ prevents chromosomal shortening and cell death in tumors
Answer: telomerase
Flashcard 8: The _____ is a Y-shaped region along the DNA template where leading and lagging strands are synthesized
Answer: replication fork
Flashcard 9: What triplet is associated with Huntington's disease?
Answer: CAG
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Flashcard 10: What triplet is associated with Fragile X syndrome?
Answer: CGG
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DNA replication Flashcards for USMLE
Study 10 flashcards on DNA replication for USMLE Biochemistry. These active recall cards cover the key concepts, clinical associations, and high-yield facts from this chapter of Molecular Genetics. Each card is designed to test your understanding rather than just recognition, building stronger and more durable memories for exam day.
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There are 10 flashcards for DNA replication, covering the key concepts, clinical correlations, and high-yield facts from this chapter of Molecular Genetics.
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