Metabolism — Flashcards

31 y/o patient present with myalgias, anorexia, & skin rash. -He doesn't do drugs or alcohol. -He has been consuming large amounts of raw egg whites for the past several months. -Physical exam: macular dermatitis of the extremities. -A water-soluble vitamin deficiency is suspected as the cause of his condition. -Which biochemical conversions most likely uses the deficient vitamin as a cofactor?

#789

A scientist is studying biochemical reaction that take place in the liver. -He cultures hepatocytes with glutamate labeled with nitrogen isotopes -After some times, he finds that the nitrogen isotopes are transferred to oxaloacetate forming aspartate. -Which vitamins is most likely involved in this reaction?

#790

What are the followings in relation to vitamin deficiency? -Abnormal oxidative decarboxylation of ketoacids. -Abnormal proline hydroxylation -Abnormal transamination -deficient methionine synthesis -Diminished synthesis of purines

Metabolism US Medical PG Flashcards - Medical Study Cards

Master Metabolism with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.

Metabolism Flashcard Deck - 10 Cards

Flashcard 781: What is the normal range of Bilirubin, serum (adult) Total?

Answer: From 0.1 to 1.0 mg/dL

Flashcard 782: What is the normal range of CSF: Glucose?

Answer: From 40 to 70 mg/dL

Flashcard 783: What is the normal range of Urine: 17-Ketosteroids, total (Male)?

Answer: From 8 to 20 mg/ 24 hr

Flashcard 784: What is the normal range of Aspartate aminotransferase (AST), serum?

Answer: From 8 to 20 U/L

Flashcard 785: What is the normal range of Urine: Sodium?

Answer: From 0 to Varies with diet mEq/L

Flashcard 786: What is the normal range of Amylase, serum?

Answer: From 25 to 125 U/L

Flashcard 787: What is the normal range of Urine: Oxalate?

Answer: From 8 to 40 ug/mL

Flashcard 788: 31 y/o patient present with myalgias, anorexia, & skin rash. -He doesn't do drugs or alcohol. -He has been consuming large amounts of raw egg whites for the past several months. -Physical exam: macular dermatitis of the extremities. -A water-soluble vitamin deficiency is suspected as the cause of his condition. -Which biochemical conversions most likely uses the deficient vitamin as a cofactor?

Answer: Pyruvate to axaloacetate. Biotin: cofactor for carboxylase reactions. because the patient has biotin (Vit. B7) deficiency due to dermatologic changes (macular dermatitis) & large consumption of raw eggs, because raw eggs contain biotin-binding avidin that loves to connect to biotin which will lead to deficiency of biotin. symptoms: mental status changes, dermatitis, metabolic acidosis due to high conversion of pyruvate to lactic acid due to lack of biotin cofactor to convert to oxaloacetate.

Flashcard 789: A scientist is studying biochemical reaction that take place in the liver. -He cultures hepatocytes with glutamate labeled with nitrogen isotopes -After some times, he finds that the nitrogen isotopes are transferred to oxaloacetate forming aspartate. -Which vitamins is most likely involved in this reaction?

Answer: Pyridoxine (vit B6) because it's a common cofactor for conversion of amino acids (glutamate) into alpha keto acid (Oxaloacetate) and convert to Aspartate (AA). (Transaminase)

Flashcard 790: What are the followings in relation to vitamin deficiency? -Abnormal oxidative decarboxylation of ketoacids. -Abnormal proline hydroxylation -Abnormal transamination -deficient methionine synthesis -Diminished synthesis of purines

Answer: Abnormal oxidative decarboxylation: Thiamine (B1) deficiency -Abnormal proline hydroxylation: vit. C deficiency -Abnormal transamination: Vit. B6 (pyridoxine) deficiency -Deficient methionine synthesis: Vit. B12 (cobalamine) deficiency. -Diminished synthesis of purines: Vit B9 (folate) deficiency

Keywords: Metabolism flashcards, medical flashcards, NEET PG preparation, USMLE Step 1 flashcards, Anki alternative, spaced repetition medical, OnCourse flashcards

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TCA cycle reactions and regulation

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Electron transport chain and oxidative phosphorylation

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Pentose phosphate pathway

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Gluconeogenesis

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Glycogen metabolism

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Amino acid metabolism

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Integration of metabolic pathways

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Fed state vs. fasting state metabolism

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Exercise metabolism

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Alcohol metabolism

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Metabolic adaptations in starvation

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Metabolic disorders overview

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