Metabolism — Flashcards

Flashcard 1331: Glycogen phosphorylase is stimulated by _____ in the liver

Answer: glucagon

Flashcard 1332: Homocystinuria can be caused by _____ deficiencies.

Answer: vitamin (B6, B9, or B12)

Extra: Classic homocystinuria is most commonly caused by an autosomal recessive deficiency of cystathionine beta-synthase (CBS). However, elevated homocysteine (and subsequent homocystinuria) can also be caused by deficiencies in B6 (pyridoxine), B9 (folate), or B12 (cobalamin).

Flashcard 1333: _____ are produced, predominantly by the liver, when growth hormones act on target tissue

Answer: Somatomedins (IGFs)

Flashcard 1334: A _____ enzyme adds inorganic phosphate onto a substrate without using ATP

Answer: phosphorylase

Flashcard 1335: Factor X of the coagulation cascade may be activated by factor _____ (extrinsic pathway)

Answer: VIIa

Flashcard 1336: In total, the TCA cycle produces _____ FADH2 per acetyl-CoA

Answer: 1

Flashcard 1337: What is the primary role of vascular endothelial growth factor (VEGF)? _____

Answer: Angiogenesis / Vasculogenesis

Flashcard 1338: What is the rate-limiting enzyme for glycogenolysis? _____

Answer: Glycogen phosphorylase

Flashcard 1339: Does the Cahill cycle result in regeneration of NAD+? _____

Answer: No

Flashcard 1340: Which lysosomal storage diseases (2) have an X-linked recessive inheritance? _____

Answer: Fabry disease, Hunter syndrome