Lipid metabolism — Flashcards

Flashcard 431: _____ is an intermediate of cholesterol synthesis that is important for N glycosylation of proteins

Answer: Dolichol PPi

Flashcard 432: Oxidized LDL has a defect in its single apoB-100 and is no longer recognized; consequently, it is consumed by _____

Answer: macrophages

Flashcard 433: Once in the vicinity of the liver, the IDL may directly bind a _____ receptor via apoprotein B-100

Answer: LDL

Flashcard 434: Which lipoprotein is secreted by intestinal epithelial cells and delivers dietary TGs to peripheral tissue? _____

Answer: Chylomicrons

Flashcard 435: The main component of chylomicrons is _____

Answer: triglycerides

Flashcard 436: Which lipid transport enzyme is responsible for the degradation of remaining triglycerides in IDLs? _____

Answer: Hepatic TG lipase

Flashcard 437: Which organ is responsible for the import and export of lipoproteins?_____

Answer: Liver

Flashcard 438: Where in the cell does cholesterol synthesis occur?

Answer: Cytosol and smooth endoplasmic reticulum (SER)

Flashcard 439: What are the two major ketone bodies produced in a type 1 diabetic patient?

Answer: Acetoacetate and beta-hydroxybutyrate

Extra: The three ketone bodies are acetoacetate, beta-hydroxybutyrate, and acetone. Acetone is produced by the spontaneous decarboxylation of acetoacetate and is considered a minor ketone body (responsible for the fruity breath in DKA).

Flashcard 440: Pulmonary surfactant is a mix of lecithins, the most important of which is _____

Answer: dipalmitoyl phosphatidylcholine (DPPC)