Lipid metabolism — Flashcards

What classes of steroid hormones are decreased in 21β-hydroxylase deficiency? _____

Hint: 2

Fat-soluble deficiencies may occur with syndromes that cause _____ (e.g. cystic fibrosis and sprue)

Cholesterol ester inside of mature HDL may be transferred to VLDL, IDL, or LDL via the enzyme _____

Type _____ hyperlipoproteinemia is also known as familial hyperchylomicronemia syndrome

What protein is responsible for the rate limiting step in steroidogenesis? _____

In the liver, bile acids are conjugated to the amino acids _____ or taurine to form bile salts

What is the mode of inheritance of type IIa familial dyslipidemia? _____

The enzyme _____ is deficient in Tay-Sachs disease

Fatty acyl-CoA is broken down into molecules of _____ via the enzyme fatty acyl-CoA dehydrogenase (β-oxidation)

What substrate accumulates in the lysosomes of a patient with Niemann Pick disease? _____