DNA repair — Flashcards

DNA repair US Medical PG Flashcards - Medical Study Cards

Master DNA repair with OnCourse flashcards. These spaced repetition flashcards are designed for medical students preparing for NEET PG, USMLE Step 1, USMLE Step 2, MBBS exams, and other medical licensing examinations.

DNA repair Flashcard Deck - 10 Cards

Flashcard 1: What are the four mechanisms of DNA repair?

Answer: Nuceotide excision repair Base excision repair Mismatch repair Nonhomologous end joining

Flashcard 2: non-homologous end joining

Answer: join 2 dsDNA ends

Extra: double-stranded breaks (when no homologous chromosome is around to use as a guide)ataxia telangiectasia

Flashcard 3: mismatch repair

Answer: 1. new strand recognized (lacks methylation) 2. mismatched nucleotides removed 3. DNA pol/ligase fills/seals gap

Extra: Mismatched bases on newly synthesized DNA strandhereditary nonpolyposis colorectal cancer (HNPCC)

Flashcard 4: base excision repair (BER)

Answer: 1. specific glycosylases recognize and remove damaged bases 2. AP endonuclease removes AP DNA 3. DNA pol/ligase fill/seal gap

Extra: spontaneous/toxic changes to the base itself; most often deamination

Flashcard 5: nucleotide excision repair (NER)

Answer: 1. endonuclease removes short ssDNA segment containing lesion 2. DNA pol/ligase fill/seal gap

Extra: bulky adducts, commonly thymine dimers caused by UV radiation xeroderma pigmentosa

Flashcard 6: Is homologous recombination error prone? _____

Answer: No

Extra: Watch associated Bootcamp video [https://app.bootcamp.com/med-school/genetics/videos/dna-mutations-damage-and-repair?index=6] https://onlinemeded.org?ref=anki

Flashcard 7: BRCA1 and BRCA2 are tumor suppresors that are involved in mediating the _____ pathway of DNA repair

Answer: Homologous Recombination

Extra: Watch Pancreatic Cancer & Islet Cell Tumors [https://dashboard.sketchy.com/study/medical/courses/medical-pathophysiology/units/medical-pathophysiology-neuro/videos/medical-pathophysiology-neuro-intracranial-hypertension-and-tumors-adult-cns-tumors?utm_source=anki&utm_medium=partnership&utm_campaign=february_update&utm_content=medical]Watch associated Bootcamp video [https://app.bootcamp.com/med-school/pathology/videos/cellular-injury-and-neoplasia?index=10] https://onlinemeded.org?ref=anki

Flashcard 8: Chronic exposure to Aflatoxins may cause cancer by causing a(n) G:C --> T:A transversion in codon 249 of the _____ gene

Answer: TP53

Extra: https://onlinemeded.org/spa/immunology?ref=anki

Flashcard 9: Aplastic anemia may be caused by Fanconi anemia, which occurs due to a(n) _____ defect, resulting in bone marrow failure

Answer: dsDNA repair

Extra: Watch associated Bootcamp video [https://app.bootcamp.com/med-school/hematology-and-oncology/videos/normocytic-anemia?index=10] https://onlinemeded.org?ref=anki Atlas: Other:

Flashcard 10: Mechanisms to repair _____ breaks are defective in Ataxia telangiectasia, Fanconi anemia, and SCID

Answer: dsDNA

Extra: Watch associated Bootcamp video [https://app.bootcamp.com/med-school/genetics/videos/dna-mutations-damage-and-repair?index=4] https://onlinemeded.org/spa/immunology?ref=anki

Keywords: DNA repair flashcards, medical flashcards, NEET PG preparation, USMLE Step 1 flashcards, Anki alternative, spaced repetition medical, OnCourse flashcards

Study by Chapter

Types of DNA damage

Flashcards

Base excision repair

Flashcards

Nucleotide excision repair

Flashcards

Mismatch repair

Flashcards

Double-strand break repair

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Homologous recombination

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Non-homologous end joining

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Direct repair mechanisms

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DNA damage response signaling

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DNA repair deficiency syndromes

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Cancer susceptibility and DNA repair

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Aging and DNA repair

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About DNA repair Flashcards for USMLE

These DNA repair flashcards are designed for USMLE Biochemistry preparation, using active recall to help you retain high-yield concepts, clinical correlations, and commonly tested facts. Each card prompts you to retrieve information from memory rather than passively reviewing notes, which research shows leads to significantly better exam performance.

The 60 cards in this deck cover the most important topics in DNA repair, including key mechanisms, diagnostic criteria, treatment protocols, and clinical pearls that frequently appear in USMLE examinations. Cards are organised by chapter so you can focus on specific areas or work through the entire topic systematically.

For personalised spaced repetition scheduling that adapts to your performance, unlimited flashcards, and detailed progress analytics, download the Oncourse app.

Frequently Asked Questions

Are DNA repair flashcards free on Oncourse?

Yes, completely free. You can study all 60 DNA repair flashcards on this page at no cost. For spaced repetition scheduling and progress tracking, download the Oncourse app.

How do flashcards help with USMLE preparation?

Flashcards use active recall — instead of passively re-reading notes, you retrieve information from memory. Research shows this builds stronger, longer-lasting memories and is one of the most effective study strategies for medical exams like USMLE.

How many DNA repair flashcards are available?

There are currently 60 flashcards for DNA repair under Biochemistry, organised by chapter. New cards are added regularly to cover the latest USMLE syllabus.

Can I study DNA repair flashcards by chapter?

Yes. The flashcards are organised by chapter so you can focus on specific areas or work through the entire topic systematically. Scroll down to the "Study by Chapter" section to pick a chapter.

What topics do these Biochemistry flashcards cover?

The cards cover high-yield concepts, clinical correlations, diagnostic criteria, treatment protocols, and commonly tested facts from DNA repair. They mirror the depth and style of USMLE questions.

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