Homocystinuria and methionine metabolism disorders — Flashcards

Flashcard 1: Vitamin B9 (folate) deficiency is characterized by _____ homocyteine levels

Answer: increased

Flashcard 2: Vitamin B9 (folate) deficiency is characterized by _____ methylmalonic acid levels

Answer: normal

Flashcard 3: Vitamin B12 and folate deficiency result in mildly elevated _____ levels, increasing risk for thrombosis

Answer: homocysteine

Flashcard 4: Which amino acids (2) have sulfur groups? _____

Answer: Cysteine, Methionine

Flashcard 5: Methyl-THF (reduced THF) is used by the enzyme _____ to convert homocysteine to methionine

Answer: methionine synthase

Flashcard 6: What stainable protein is abundant in astrocytes?

Answer: GFAP

Flashcard 7: What enzyme converts pyruvate to alanine?

Answer: alanine aminotransferase (ALT)

Flashcard 8: myeloperoxidase

Answer: respiratory burst

Extra: H2O2HOClPMNs

Flashcard 9: superoxide dismutase

Answer: respiratory burst

Extra: O2-H2O2

Flashcard 10: The Golgi makes modifications to some amino acids trafficking through it. What are the modifications made to threonine?

Answer: O-oligosaccharide