Rheumatology & Haematology — Flashcards

Flashcard 81: Chronic kidney disease causes _____cytic normochromic anaemia from ↓ production of erythropoietin (EPO)

Answer: normo

Flashcard 82: Minimal change disease is rarely associated with _____

Answer: Hodgkin lymphoma

Flashcard 83: Loss of _____ in nephrotic syndrome results in a hyper-coaguable state

Answer: antithrombin III

Flashcard 84: What result is associated with good prognosis in RA?

Answer: • Rheumatoid factor negative

Flashcard 85: What is the antidote for Methotrexate overdose?

Answer: • Folinic Acid

Flashcard 86: What imaging is required for a Rheumatoid Arthritis (RA) patient before undergoing surgery with general anesthesia/intubation?

Answer: Anteroposterior and lateral cervical spine radiographs (Flexion/Extension views) to screen for atlantoaxial subluxation.

Extra: Patients with Rheumatoid Arthritis (RA) are at risk for atlantoaxial (C1-C2) instability due to erosion of the transverse ligament and odontoid process. Pre-operative assessment is crucial before intubation to prevent spinal cord injury during neck manipulation.

Flashcard 87: What cardiovascular disease do RA patients have an increased risk of?

Answer: • IHD due to systemic inflammation

Flashcard 88: What complication can arise if Trimethoprim is prescribed alongside methotrexate?

Answer: • Bone marrow supression • Severe or fatal pancytopaenia

Flashcard 89: What Investigation do you need to order before prescribing Biologics in RA?

Answer: Chest X-Ray To look for TB prior to starting biologics for RA, as they can cause reactivation

Flashcard 90: What is Systemic Sclerosis?

Answer: • An automimmune connective tissue disease involving inflammation and fibrosis of the connective tissues, skin and internal organs