Rheumatology & Haematology — Flashcards

Flashcard 751: If PMR is the most likely diagnosis then it should be managed with _____

Answer: prednisolone 15mg OD

Extra: The typical starting dose for Polymyalgia Rheumatica (PMR) is 15mg prednisolone daily. A prompt response (usually within 48-72 hours) supports the diagnosis.

Flashcard 752: If patients with suspected PMR do not respond substantially to _____, consider an alternative diagnosis

Answer: prednisolone

Flashcard 753: What investigations should be ordered for suspected psoriatic arthritis? _____, inflammatory markers, Rheumatoid factor, Anti-CCP

Answer: X-ray of hands and feet

Flashcard 754: Patterns of psoriatic arthritis: • _____ - most common; resembles rheumatoid arthritis • Asymmetrical oligoarthritis - usually affects hands and feet • Distal interphalangeal (DIP) disease - classic but occurs in ~10% • Sacroiliitis - spondylitis-like; involves spine and sacroiliac joints • Arthritis mutilans - severe/rare; characterized by telescoping of digits (pencil-in-cup deformity)

Answer: Symmetrical polyarthritis

Flashcard 755: Psoriatic rashes are typically found on _____ surfaces

Answer: extensor

Flashcard 756: Psoriatic arthritis is often associated with additional features such as _____, nail changes, dactylitis, enthesopathy

Answer: rash

Flashcard 757: What is the management of psoriatic arthritis after symptomatic relief? 1st line: _____ 2nd line: Biological DMARDs - e.g. anti-TNF 3rd line: Targeted synthetic DMARDs - e.g. Tofacitinib

Answer: Conventional synthetic DMARDs

Flashcard 758: Psoriatic arthritis is a _____ spondylarthropathy

Answer: seronegative

Flashcard 759: Polymyalgia rheumatica typically presents with _____ & morning stiffness of the proximal limb muscles

Answer: aching

Flashcard 760: What investigations should be ordered as part of a polymyalgia rheumatica diagnosis? _____, Creatinine kinase

Answer: Inflammatory markers (e.g. ESR, plasma viscosity, CRP)