Rheumatology & Haematology — Flashcards

Flashcard 671: Multiple myeloma most commoly occurs in _____

Answer: the elderly (60-70)

Flashcard 672: _____ impairment associated with myeloma is a result of light chain deposition within the tubules

Answer: Renal

Flashcard 673: Myeloma may cause decreased production of _____ which leads to an increased susceptibility to infection

Answer: normal immunoglobulins

Flashcard 674: _____ presenting with unexplained lymphadenopathy should be considered for a very urgent 48 hr referral for lymphoma

Answer: Children and young people

Flashcard 675: What are the 2 types of Bence-Jones proteins? _____

Answer: Lambda and Kappa

Flashcard 676: The features of myeloma can be memorised using the CRABBI mnemonic: _____

Answer: HyperCalcaemia Renal involvement Anaemia Bleeding Bones Infection

Flashcard 677: FBC in a patient with Hodgkin's lymphoma may show _____, lymphocytopenia and eosinophilia

Answer: normocytic, normochromic anaemia

Flashcard 678: End stage progression of myeloma may be reduced with long term use of _____

Answer: bisphosphonates

Flashcard 679: The most common site of _____ involvement in lymphoma is the Gastrointestinal (GI) tract (specifically the stomach)

Answer: extranodal

Extra: Primary sites of lymphoma are the lymph nodes. When it occurs outside the nodes (extranodal), the GI tract is #1, followed by the skin. The spleen and liver are common sites of systemic involvement (stage IV disease) but not the most common extranodal sites overall.

Flashcard 680: Hodgkin's lymphoma with _____ lymph node involvement may experience dyspnoea or chest pain

Answer: mediastinal