Rheumatology & Haematology — Flashcards
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Vitamin B12 deficiency is predominantly caused by _____ issues
Hint: dietary/malabsorption
Patients with pernicious anemia should be monitored for development of _____ cancer
What specific investigations are done for pernicious anaemia? _____ Anti-intrinsic factor antibody test
Vitamin B12 deficiency presents with _____ symptoms ± neurological symptoms
Pernicious anaemia blood smear will show _____ polymorphonuclear cells
On examination patients with vitamin B12 can have _____
Hint: tongue finding
_____ deficiency = ↑ homocysteine + ↑ methylmalonic acid (MMA) Folate deficiency = ↑ homocysteine + normal/↓ methylmalonic acid (MMA)
Vitamin B12 deficiency will have anaemia presenting with _____, pallor, and shortness of breath
What is the management of pernicious anaemia? _____ vitamin B12
Hint: route of administration
Patient with suspected folate deficiency is treated with folic acid, but then develops rapidly progressive neurological deficits. What is going on? _____
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