Rheumatology & Haematology — Flashcards

Flashcard 51: What is the first-line for Knee Osteoarthritis?

Answer: • topical NSAIDs

Flashcard 52: What location is a red flag in back pain?

Answer: • Thoracic pain

Flashcard 53: Psoas abscess is an important differential for back pain in which patient group?

Answer: • IVDU

Flashcard 54: What investigation is used to diagnose pernicious anaemia?

Answer: • Intrinsic factor antibody titre

Flashcard 55: What is used to manage acute flares of Rheumatoid Arthritis?

Answer: NSAIDs and/or Corticosteroids (e.g., Oral prednisolone or IM methylprednisolone)

Extra: Corticosteroids are often used as 'bridging therapy' when starting or escalating DMARDs to provide rapid symptomatic relief during a flare.

Flashcard 56: Infectious mononucleosis is transmitted via _____

Answer: saliva

Flashcard 57: Infectious mononucleosis typically has _____ pharyngitis/tonsilitis

Answer: exudative

Flashcard 58: Pharyngitis/tonsilitis in infectious mononucleosis treated with _____ often results in a(n) maculopapular rash

Answer: aminopenicillins

Flashcard 59: What is the likely diagnosis in a teen with 3-day history of fever, exudative tonsils, posterior cervical lymphadenopathy, & splenomegaly O/E. There is lymphocytosis on FBC and a -ve monospot test. _____

Answer: Infectious mononucleosis

Flashcard 60: What would Bone Marrow Aspirate show in multiple myeloma?

Answer: > 10% plasma cells (clonal)

Extra: Diagnostic criteria for Multiple Myeloma requires clonal bone marrow plasma cells ≥10%. Morphology may show: • 'Fried egg' appearance • Mott cells (multiple cytoplasmic droplets) • Russell bodies (cytoplasmic inclusions) • Flame cells (IgA myeloma)