Rheumatology & Haematology — Flashcards

Flashcard 481: Systemic lupus erythematosus (SLE) may affect the brain, causing _____ or psychosis

Answer: seizures

Flashcard 482: SLE clasically presents with _____, malar rash ("butterfly rash"), & constitutional symptoms

Answer: arthritis

Flashcard 483: _____ ethnicity is more commonly affected by SLE

Answer: African

Flashcard 484: SLE patients have a life expectancy approx. _____ years shorter than the general population.

Answer: 15-25

Flashcard 485: The characteristics of _____ may be remembered with the mnemonic "RASH OR PAIN": Rash (malar or discoid) Arthritis (usually involving ≥ 2 joints) Serositis (pleuritis and pericarditis) Hematologic disorders (e.g. cytopenias) Oral or nasopharyngeal ulcers (usually painless) Renal disease Photosensitivity Antinuclear antibodies Immunologic disorder (anti-dsDNA, anti-Smith, antiphospholipid) Neurologic disorder (seizures, psychosis)

Answer: systemic lupus erythematosus (SLE)

Flashcard 486: _____ typically presents as erythematous, scaly plaques with follicular plugging and central scarring/atrophy.

Answer: Discoid Lupus Erythematosus (DLE)

Extra: Discoid Lupus Erythematosus (DLE) features: • Well-demarcated erythematous plaques. • Adherent scale that extends into hair follicles (follicular plugging/carpet tack sign). • Central atrophy, scarring, and telangiectasia. • Most common on sun-exposed areas (face, scalp, ears). • Only 5-10% of DLE patients progress to Systemic Lupus Erythematosus (SLE).

Flashcard 487: In SLE, levels of _____ are decreased during active disease (flares) due to consumption.

Answer: C3 and C4

Flashcard 488: Purine-rich food such as _____ & sea food cause ↑ uric acid production thus can precipitate gout

Answer: red meats

Flashcard 489: Gout more commonly affects _____ 3:1

Answer: men

Flashcard 490: _____ is a crystal arthropathy caused by monosodium urate crystals forming in synovial joints and tissues

Answer: Gout