Rheumatology & Haematology — Flashcards

Chronic lymphocytic leukaemia may transform into _____ via the Richter transformation

Acute lymphoblastic leukaemia is subclassified into _____-ALL and T-ALL based on surface markers

Hint: ~85%

Chronic lymphocytic leukaemia typically presents asymptomatically but can cause _____ symptoms

_____ is a myeloproliferative disorder that leads to bone marrow fibrosis, extramedullary haematopoiesis, & splenomegaly

Which blood transfusion reaction is a reaction against donor plasma proteins in transfused blood? _____

What is the likely diagnosis in a patient that develops respiratory distress, hypertension, tachycardia and signs of a heart failure 6-12 hours after a RBC transfusion? _____

Hint: diagnosis?

Which blood transfusion reaction can be caused by accumulation of cytokines from donor WBC -or- type II HSR with host antibodies against donor HLA/WBCs? _____

_____ myelofibrosis occurs as a result of disease progression in patients with previously diagnosed myeloproliferative disorder (e.g. PV, ET)

What are the bone marrow aspiration finding(s) for myelofibrosis? _____

What is the management of febrile non-haemolytic transfusion reactions? _____