Rheumatology & Haematology — Flashcards

Suspect _____ in patients with sickle cell disease that have LUQ tenderness, hypovolaemic shock, & splenomegaly

In sickle cell disease, the spleen becomes dysfunctional in _____ ("splenic fatigue")

Hint: demographic

What is the most common cause of paediatric stroke? _____

Sickle cell disease can cause _____ due to vaso-occlusion of cerebral vessels

_____ is typically the earliest manifestation of sickle cell disease in infants <5yrs old

Acute haemolytic crisis in sickle cell disease may require _____

Hint: management

Sickle cell disease can be complicated with _____ from encapsulated organisms causing sepsis, pneumonia, & meningitis

Sickle cell disease and fever is managed with _____

Hint: next step

_____ is considered in severe vaso-occlusive crisis/events, e.g. acute chest syndrome or stroke

Hint: Management

What RBC pathology is characterised by the following Hb electrophoresis findings: 90% HbS, 8% HbF, and 2% HbA2 (no HbA) _____