Neurology — Flashcards

As Parkinson disease progresses, the therapeutic window for levodopa _____ and response becomes more unpredictable

What is the management of Parkinson's once medical therapy is exhausted? Consider _____

Peripheral conversion of _____ can cause N&V, tachyarrhythmias, postural hypotension

Hint: Parkinson drug

What is the first-line management for Parkinson's disease if motor symptoms impact QOL*? _____

Parkinson's disease is a _____ diagnosis with the UK Parkinson's Disease Society Brain Bank Clinical Diagnostic Criteria

_____ is a precursor of dopamine that does cross the blood-brain barrier

What is the management for Parkinson's disease where the patient has developed dyskinesia and/or motor fluctuations? Offer _____, MAO-B, or COMT inhibitors in adjunct to levodopa Then consider amantadine if resistant

Chronic levodopa use can cause a(n) "_____ phenomenon", with unpredictable periods of akinesia (off) alternating with periods of improved mobility (on)

What is the first-line management for Parkinson's disease in early stages & motor symptoms do NOT impact QOL*? _____

Parkinson's disease presents with _____lateral & asymmetric motor signs