Gastroenterology & Hepatology — Flashcards

Flashcard 621: The cause of Crohn's disease is unknown, but there is a strong _____

Answer: genetic susceptibility

Flashcard 622: Smoking results in: _____ risk for Crohn disease ↓ risk for Ulcerative colitis

Answer: ↑

Flashcard 623: When are antibiotics used in perianal abcesses? _____

Answer: If there is systemic upset secondary to the abscess.

Extra: Antibiotics are generally **not** required after I&D of a simple perianal abscess unless there is: 1. Systemic upset (fever, sepsis) 2. Significant spreading cellulitis 3. Diabetes or immunosuppression 4. Risk of endocarditis (valvular heart disease)

Flashcard 624: Symptoms of ulcerative colitis include: _____ urgency, episodic/chronic diarrhoea (+ blood and mucus); and crampy discomfort (not pain).

Answer: bowel

Flashcard 625: What is the **1st-line** medical management for **inducing remission** in Crohn's disease?\n_____

Answer: Glucocorticoids (e.g., Prednisolone or Budesonide)

Extra: 5-ASA drugs (e.g., Mesalamine) have limited efficacy in Crohn's disease and are generally not recommended for induction, unlike in Ulcerative Colitis where they are 1st-line. Glucocorticoids (Prednisolone or Budesonide) are the standard first-line choice for inducing remission in Crohn's.

Flashcard 626: Which form of inflammatory bowel disease is characterized by pseudopolyps? _____

Answer: Ulcerative colitis

Flashcard 627: Acutely thrombosed external haemorrhoids typically present with _____ and appear purplish & oedematous

Answer: significant pain

Flashcard 628: What is the management for maintaining remission in Crohn's? 1st-line: _____ or mercaptopurine

Answer: Azathioprine

Flashcard 629: Crohn disease is characterised histologically by lymphoid aggregates with _____

Answer: noncaseating granulomas

Flashcard 630: Perianal abscesses can be caused by underlying IBD, especially _____

Answer: Crohn's