Renal Physiology — Flashcards

Some _____ in the cells of the thick ascending limb diffuse back into the lumen, creating a lumen positive potential difference

In response to increased Na+ delivery (e.g. increased GFR/RPF), the macula densa releases _____, which constricts the afferent arterioles

In the presence of _____, aquaporin 2 channels are inserted in the luminal membrane of principal cells of the late distal tubule and collecting duct

The H2CO3 formed inside the cells of the PCT dissociates into _____ and HCO3-

HCO3- is transported across the basolateral membrane into the blood by:\n1. Proximal tubule: _____\n2. Alpha-intercalated cells: Cl--HCO3- exchange

In the _____ of ADH, free-water clearance (CH2O) is positive

Na+ is reabsorbed in the _____ via the Na+-K+-2Cl- cotransporter in the luminal membrane

How does ADH increase H2O permeability of the principal cells of the late distal tubule and collecting duct?Increased _____ channels via increased cAMP

In the _____ of the nephron, urea is secreted by simple diffusion

In the cells of the proximal tubule, the enzyme _____ metabolizes glutamine to glutamate and NH4+