Endocrinology — Flashcards

Chronic excess levels of cortisol (glucocorticoid) result in decreased levels of _____ and ACTH via negative feedback

Increased ATP:ADP ratio in the pancreatic beta cell (as a result of glucose metabolism) causes ATP-sensitive _____ channels to close, causing membrane depolarization

Vasopressin (ADH) causes _____ of arterioles by activating V1 receptors

_____ puberty, excessive levels of growth hormone cause gigantism (increased linear growth)

When insulin acts on adipose tissue, it causes _____ triglyceride storage and decreased lipolysis

PTH action causes increased urinary _____ and phosphat-uria

High levels of _____ inhibit organification of I2, and therefore inhibit synthesis of thyroid hormones (Wolff-Chaikoff effect)

The _____ effect is the inhibition of thyroperoxidase by excess iodine

Thyroid, Pituitary, & Adrenal _____ stimulates the liver to produce IGF-1

The hormone sensitivity (responsiveness) of a target tissue may be changed in two ways: 1. Change the _____ of receptors 2. Change the affinity of receptors