Compartment Models — Flashcards

The nomogram used for vancomycin dosing is the _____ nomogram.

Which parameter is used to asses the extent of drug absorption in a plasma concentration vs. time graph?_____

In first-order kinetics, a drug infused at a constant rate takes _____ - 5 half-lives to reach steady state

Phenytoin follows _____-order kinetics at lower concentrations. As the concentration increases, the elimination changes to zero-order kinetics.

Time for peak plasma concentration (Tmax) of a drug indicates the rate of _____ from the administered site.

The loading dose of a drug is governed primarily by its _____

What formula is used to calculate loading dose? _____

What formula is used to calculate half-life in first-order elimination kinetics? _____

What formula is used to estimate volume of distribution (Vd)? _____

What formula is used to calculate maintenance dose? _____