Endocrine Pharmacology — Flashcards

Flashcard 141: Drug of choice for pre-operative medical preparation of a hyperthyroid patient for thyroid surgery to achieve a euthyroid state

Answer: Carbimazole (or Methimazole)

Extra: Antithyroid drugs like Carbimazole or Methimazole are used for 4–6 weeks to render the patient euthyroid before surgery. Lugol's iodine or potassium iodide is typically added 7–10 days pre-operatively to decrease the vascularity and friability of the thyroid gland.

Flashcard 142: What is the drug of choice for treatment of central precocious puberty? _______

Answer: Leuprolide acetate

Flashcard 143: Drug of choice for acute adrenal insufficiency is?

Answer: Hydrocortisone

Flashcard 144: Drug of choice for the treatment of hyperthyroidism in pregnancy is:

Answer: Propylthiouracil (1st trimester)

Flashcard 145: Drug of choice as antidiabetic in obese patient:

Answer: Metformin

Flashcard 146: Drug of choice for hyperthyroidism during 2nd and 3rd trimester of pregnancy is:

Answer: Methimazole

Extra: • 1st trimester DOC: Propylthiouracil (PTU) - used during organogenesis to avoid Methimazole embryopathy (e.g., aplasia cutis). • 2nd and 3rd trimester DOC: Methimazole - preferred for the remainder of pregnancy to avoid the risk of PTU-induced severe hepatotoxicity.

Flashcard 147: Drug of choice for central diabetes insipidus

Answer: Desmopressin

Flashcard 148: Drug of choice for diabetic ketoacidosis to control hyperglycemia is _______ insulin

Answer: Regular insulin

Flashcard 149: Drug of choice for Insulinoma is

Answer: Diazoxide